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Platform for studying stem cells will try

A team of Canadian researchers has developed an automated platform for microfluidic cell culture to monitor the growth, survival and response to the hundreds of hematopoietic stem cells (HSCs, for its acronym in English) at the cellular level. The discovery is published Sunday, May 22, edition 'on line' in the journal 'Nature Methods'.

This new tool will allow scientists to study multiple variables in culture conditions simultaneously time and get new insights into the growth factors necessary for cell survival Hematopoietic stem.

According to the leader of this study, Véronique Lecault, Department of Chemical and Biological Engineering University of British Columbia (UBC) in Canada, "the ability to perform massively parallel cultures of mammalian cells could provide new avenues for explore complex biological questions. "

"Our results will be used in many applications such as drug development, the selection of clones and optimization of crops," says Lecault.

The HSCs are found primarily in the bone cord and have an amazing ability to maintain a continuous production of specialized blood cells .

These cells have important clinical utility, especially for the treatment of cancer and blood-borne diseases. But the regulatory mechanism of stem cell division (self-renewal) or more mature cells (differentiation) is still not well understood.

The heterogeneous nature of the hematopoietic population complicates the study of HSCs, hiding the individual responses of mean measurements. The study of individual cells is therefore key to understanding these mechanisms. However, current techniques require hard work, expensive reagents and has limited flexibility to characterize the cells or changing the culture conditions.

The Canadian research team has designed and fabricated a microfluidic device - about the size of a matchbox - containing between 1,600 and 6,400 miniature culture chambers that can hold an important cell growth, together with sequential imaging system to control clones for several days while they develop from single cells.

Source: europapress.es

Stem Cells

will try

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hematopoietic stem cell lateral sclerosis

lateral sclerosis stem cell

The Israel Ministry of Health has approved laboratories BrainStorm Cell Therapeutics Inc. to begin testing cell therapies mother in patients with amyotrophic lateral amniotrófica.

scientists BrainStorm For this trial represents a major advance in the conquest of the goal of using stem cells to begin with the idea of \u200b\u200bneuronal recovery in the treatment of amyotrophic lateral amniotrófica, as indicated by Adrian Harel, one of loslíderes of the company.

With this new license, patients suffering from amyotrophic lateral amniotrófica start receiving your own stem cells from bone marrow, and subjected to treatment with NurOwn technology, which received orphan drug designation (drug to diagnose, prevent or treat a disease) by the Food and Drug Administration.

Participants in the study of stem cells be divided into two groups, one with patients who have a high degree of disease and others who suffer early.

The patient follow-up will take about 6 months. (With information from La Jornada)

Source: sumedico.com

will try lateral sclerosis stem cell

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umbilical cord blood to detect food intolerances

umbilical cord blood to detect food intolerances

ivity, bank stem cells from umbilical cord IVI Group, has launched a genetic test that can detect if the baby will food intolerances.

The test involves removing a sample umbilical cord blood obtained at the time of delivery. Thus, from a genetic study, can detect whether the child will develop some of the most common food intolerances.

Thus, if results are positive may initiate preventive measures. Otherwise, if you are poor, may introduce new foods into your baby's diet with greater ease and safety of tolerability.

"This genetic test involves no nuisance the mother and provides a very important and useful information during the first months of baby's life, when can shed some light on the problems associated with food intolerances, "says managing director ivity, Alfonso Sanchez.

About 10 percent of children develop during childhood staple food intolerances in the diet such as lactose, fructose or gluten.

Source: europapress.es

umbilical cord blood to detect intolerances food

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discovered a new cell in the human body

open lung stem cells a way to treat respiratory diseases. The research may help us understand how causes lung cancer. The Harvard team hopes to treat emphysema and pulmonary hypertension. The treatment is not yet ready for testing in people

Researchers at Harvard Medical School (USA) have discovered a cell type previously unknown in the human body. This is stem cells of the lungs, as has been demonstrated in a series of experiments, have the ability to regenerate damaged lungs. From these stem cells can form not only different types of cells that make up a lung, but also the blood vessels supplying the respiratory system.

Research is a step ahead of understanding how lung diseases originate. Of these, lung cancer is the leading candidate to be related to alterations of stem cells.

On the other hand, the research paves the way for developing new treatments for respiratory diseases utilizing the capacity that have shown stem cells to regenerate lung tissue.

"We believe that these cells have the potential used against a wide range of lung diseases including emphysema (which causes severe respiratory failure) and pulmonary hypertension, "said Joseph Loscalzo, co-author, by email. The treatment would remove a sample of lung tissue from patients, isolating the stem cells multiply in the laboratory and re-entered in the lungs to regenerate damaged. Because these cells would have been obtained from patient's own tissue, not cause immune rejection.

A potential test of lung stem cells is that the findings were presented today The New England Journal of Medicine, a journal specializing in publishing research that change the way medicine is practiced. For now, however, these cells have regenerated only in mice lungs, so they are not ready for use in humans.

Harvard researchers to identify the lung stem cells has been like finding the needle in the haystack. Since lung tissue that had been donated for transplantation and were not used, and lungs of fetuses that had died, the researchers looked for cells that have a protein called c-kit. They focused on this protein because, in the heart, to identify cardiac stem cells.

In the lungs, they found, only one in 6,000 cells of the bronchioles, and one of every 30,000 of the alveoli, are the protein c-kit (see chart). These few cells isolated and cultured in the laboratory. Noted that had the ability to divide as do stem cells, producing one hand a new stem cell and, secondly, a differentiated cell lung characteristic.

After producing hundreds of thousands of these cells, inoculated mice with lung injuries. Each mouse received about 20,000 cells human. After two days, 25% of these cells had been implanted in the lungs of mice and were dividing. After two weeks, the cells had restored bronchioles, alveoli and blood vessels. An analysis confirmed that the regenerated tissue was composed of human cells, which were integrated with the normal tissue of mice.

Previous studies have identified progenitor cells can give rise to more specialized cells in different regions of the lungs. But this is the first identified a stem cell can form any cell type lung.

"It's a spectacular research," said Thomas Graf, ICREA researcher who heads the group of stem cell research at the Centre for Genomic Regulation (CRG). "If these results are replicated in other laboratories, opening the way to propose autologous (own cell) for patients with respiratory diseases."

Ángel Raya, ICREA researcher and stem cell specialist at the Institute of Bioengineering of Catalonia (IBEC), agrees that "the first thing to do is reproduce the data in other laboratories" so that these stem cells can be used medical purposes.

Harvard team plans to repeat the research in animals other than mice tested in people before a treatment based on stem cells in the lungs. "We'll try it in a large animal model in the near future. Is a necessary step before considering a clinical trial in people, "said Piero Anversa, director of research, e-mail.

Another issue that should be studied, Anversa says, is what is the best way to get stem cells from patients and re-administered after they have been multiplied in the laboratory. Direct injection cells in the lungs that has been used in research on mice could be impractical in humans. As alternatives, the Harvard team contemplates the possibility of administering the cells by a bronchoscopy, which allows access to a thin tube into the lungs, or by inhalation with a nasal spray.

The different types of stem cells

ADULT

have ability to form specific cells or tissues such as lung stem cells identified now. Its medical use dates back to 1959, when it became the first transplant bone marrow. The advances of the last decade have renewed interest in them.

EMBRYONIC

have the capacity to become any cell in the body. U.S. scientists discovered in 1998 how to grow embryonic stem cells in the laboratory, which stimulated this research area and provoked fierce ethical debate.

IPS

iPS cells are derived from adult cells but behave like embryonic stem cells by genetic reprogramming technique introduced in 2006 by researcher Japan's Shinya Yamanaka. This technique avoids the ethical debate of embryonic stem cells.

Source: lavanguardia.com

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develop liver cells from stem cells

Researchers at the School of Medicine, Johns Hopkins University in Baltimore (USA) have succeeded in producing liver cells from human induced pluripotent stem cells. The results of the study are published in the journal Science Translational Medicine.

The findings open the way to the development of new therapies with stem cells liver for many patients who have run out of options because lack of liver tissue donation for transplantation. By producing an ample supply of liver cells can be transplanted to patients without risk of immune rejection, stem cell therapy could save lives.

The problem with stem cell therapy is that adult stem cells are difficult to isolate or produce in culture. But the cells induced pluripotent stem (iPS cells) can be generated from small amounts of tissue from patients and can occur indefinitely in culture. Thus, liver cells, iPS cells derived from specific patient can be generated not only in large quantities but also for each patient, avoiding immune rejection problems associated with incompatible donor liver or embryonic stem cells.

reprogramming process can become induced pluripotent stem cells (iPS cells) from skin or blood cells, liver cells capable of repairing damaged liver tissue.

Scientists human iPS cells generated from a variety of adult human cells, including fibroblasts, bone marrow cells and skin cells and showed that the internal structures of cells or molecular scenarios are similar and stem cells. Then the researchers "taught" to human iPS cells to first become mature liver cells, using a set of procedures that mimic the different stages of liver development. Regardless of the origin of tissues, human iPS cells showed all the same capacity to differentiate into liver cells.

Researchers went to a mouse model of liver disease and evaluated the liver cells derived from human iPS cells for their ability to regenerate liver tissue.

The authors found that liver cells derived from human iPS cells grown in fresh mouse liver with an efficiency of between 8 and 15 percent. The new liver cells were also fully functional, proteins secreted by normal liver cells were detected in the blood of mice was transplanted liver cells derived from human iPS cells.

Although the results indicate that readily available tissues such as skin or blood could help heal the damaged liver, further studies are needed they can use liver cells derived from human iPS cells.

Source: europapress.es

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Curan

Hospital Universitario Central de Asturias (HUCA) has managed to heal pressure ulcers and 19 of the 22 paraplegic patients included in clinical trials with stem cells bone marrow. The research just published in the journal "The Journal of Spinal Cord Medicine." According to the authors, this is the first stem cell treatment designed in Spain and one of the first in the world, which is effective for typical fistulas (or "sores") often experienced by people confined to bed and reduced mobility and can easily get to be a difficult problem.

The test was carried out by the coordination unit transplantation and cell therapy HUCA. The first signatories of the article are Sarasu Julian Gonzalez, chief of plastic surgery department, who is retiring the same day, "and Silvia López Pérez, biologist of that unit. The other signatories of the article are Jesus Otero, director of the transplant unit and cell therapy, "Dolores Escudero, Coordinator HUCA transplants, biologists María Álvarez Viejo, Marcos Perez and Yolanda Menéndez, hematologists Angeles Gala Fernandez and Jose Garcia, Amaia Ferrero biochemistry, and the plastic surgeon Ángel Pérez Arias.

"It is estimated that at least 85 percent of paraplegic patients developed pressure ulcers at some point in their lives", explained yesterday to THE NEW SPAIN Silvia Perez, who added that injuries of this type are difficult treated with conventional therapy, so that "often become a chronic and highly recurrent."

The team of Central Hospital of Asturias began its work by similar investigations of other groups that had reaped positive results with bone marrow stem cells applied to chronic wounds. None of them had been held in Spain. The trial, funded by the FICYT-focused on paraplegic patients. Specifically, in 22 patients (19 men and 3 women) with a mean age of 56 years presenting with severe pressure ulcers and more than four months. They shared that they had not responded to topical treatment. Thirteen of them had previously undergone surgery without positive results.

Silvia

Perez explains how processes were developed. Eligible patients were subjected to a puncture of the iliac crest to obtain mononuclear cells by density gradient. After three hours of collection, and once processed and purified cell fraction desired, this product was inoculated to the patients in the operating room, where shortly before the arrival of the cells had undergone minimal surgical intervention consisting of a cleaning and debridement of the wound with saline. Then the wound margins were united by suture, creating a space in which the suspension was inoculated Cell.

HUCA multidisciplinary team concluded that cell therapy designed for the test is a very valid option for the treatment of pressure ulcers in type IV, the most serious, those in which there is necrosis of muscle , bones, joints and surrounding tissues.

Hospital Universitario Central de Asturias (HUCA) launched a few years ago three clinical trials based on the use of stem cells. One of them was the use of pancreatic islets for diabetes sufferers. Started yielding good results, but the bottom line was not satisfactory. The other focuses on the application of stem cells to infarcted hearts, the results have not been published yet.

Source: lne.es

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skin stem cells Stem Cells Pat

• Several groups investigated in English therapies with adult stem cells
• may be used to close wounds and ulcers or various diseases

The cells drugs are as alive and intelligent s: have a great ability to solve different problems, but they are uncontrollable and unpredictable if not perfectly know what you're doing. Currently, There are about 3,000 clinical trials of cell therapy in the world, but only about 100 have reached Phase 3, ie, have a significant number of patients. Most of them also belong to the field of hematology, pioneered the use of cells, particularly those of bone-marrow to treat diseases such as leukemia or lymphoma.

Outside this area, which actually has decades of advantage over other forms of cell therapy, studies that have reached their final stage can be counted on the fingers. "Right now, nobody has successfully completed a Phase 3 with stem cells other than hematology. But they are bound for a long time: the novelty lies in the non-haematological cells, to treat non-hematologic diseases, "says Damián García Olmo, director of the Cell Therapy Group of La Paz Hospital in Madrid.

These

are just some of the studies that, with due respect to scientific protocols, are ongoing in Spain in the field of cell therapy applicable to a wide range of disorders and diseases. In some cases is more advanced, in others it begins now experience and, sometimes, be has begun to treat patients, but all are significant to the future: where is the cell and tissue transplantation:

Degenerative

José María Moraleda, Professor of Hematology at the University of Murcia and coordinator of the Cell Therapy Network, is working at the Hospital Virgen de Arrixaca (Murcia) for five years in a clinical trial to treat amyotrophic lateral sclerosis (ALS), degenerative disease afflicting the physicist Stephen Hawking. "We have passed the stage of showing that cells with the method we use are safe, and now we are trying to prove its effectiveness." The idea is to inject these 'living drugs' within the spinal cord (the neural tissue that transmits nerve impulses), using various procedures and check the patients' motor skills improve. "The next phase will allow us to see if cell transplantation has a positive effect," the expert adventure.

So far, it has been observed in laboratory mice with sporadic ALS (the most common variant of the disease) that the specimens treated cells survive longer and the process of paralysis progresses more slowly. "The infusion of cells protects motor neurons (responsible for movement) to to survive longer and better, "Moraleda said.

Repair scars

Damián García Olmo, head of Colorectal Surgery and director of the Cell Therapy Group of the Hospital La Paz, wants to use cell transplants for solve one of the great problems of surgery: healing. To do this, nothing better than going to an extreme case and see if therapy can help: "We chose as a model perianal fistula [an abscess that connects the anal canal skin abroad] because it is the most difficult to heal, especially in patients with Crohn's disease [inflammation of the bowel caused by an autoimmune process] " García Olmo said. "We had some problems, we have learned and I think within the next four or five years, we have results applicable to surgery," he adds.

Other studies are testing similar procedures but applied to myocardial infarction, a treatment that also could benefit from tissue regeneration using stem cells, says García Olmo. "And the third major group of diseases is the world of traumatology and orthopedics," says the researcher. The procedure, with its many nuances, Recobeco and difficulties, is always the same: to regenerate damaged tissues by implanting cells with the capacity to differentiate into the 'medicine' necessary.

Repair

cornea transplant cornea common, which involves removing the eye tissue of a dead donor and implant it into the patient, is already an established clinical practice. However, sometimes fails because this tissue needs to be renewed every day, through a niche stem cells called limbo. If the limb is in bad shape, the cornea is no longer transparent and the patient loses vision. Ana Sanchez, Professor of Physiology at the University of Valladolid, and his group take a decade working with stem cells, and are currently transplanting and patient's own stem cells in the limbus of the cornea so that it can renew itself and avoid the above problem.

"If there is a healthy eye, we take a biopsy of the limbus and grow in the laboratory on a membrane that is placed like an eye patch. Lens is placed so as not to move, the days are removed and the cells are in limbo, "says Sanchez. "If the injured patient has two eyes, we must resort to a corpse, the cells are from another person and must be used immunosuppressive agents, but as the limb is poorly vascularized, usually works well" explains. "We had 30 patients with 80% of success."

Breast Reconstruction

César Casado, head of the department of Plastic, Reconstructive and Aesthetic Surgery of the Hospital La Paz, Madrid, working with fat cells taken from the patient's own skin through a process of pumping and spin . Once the cells are separated from adipose tissue, can be used in plastics that require different treatments to rebuild or improve parts of the anatomy, including the face. "I would have many aesthetic possibilities," says this expert, who adventure "breast reconstruction of the future [for patients who have overcome breast cancer] is going to go around. "

fat cells could also be very useful for patients with facial atrophy, either congenital or acquired. A major advantage of this system is speed, because the fat is infiltrated within hours. Moreover, "because they are not aggressive patient's own cells," said Casado, although he admits that more experience is needed to control the degree of absorption and implantation of the cells.

skin Cultivating

Married The team doctor also works on the skin culture in the laboratory, to treat patients who have suffered accidents or burns. The process "cumbersome and very expensive," involves removing inches from the patient's healthy skin, you can get back or other areas that have not been affected, then this tissue grown in the laboratory to multiply its size. The skin, which can also be extracted from a cadaver donor, processed in a kind of mesh with knives, and once that has produced the required amount can be implanted in the patient to repair other damage.

Ana Valladolid Sanchez and his team also work on projects to regenerate the skin and in the design of artificial bone cartilage. The latter would apply in plastic and maxillofacial surgery, to replace the nose or ear, for example, in patients who have been victims of tumors or accidents. "We make a matrix with cells from the patient and can be molded. If I make a mold of your ear, I have an ear," says the doctor. For now, these projects are in experimental stage, even with animals. The infusion of cartilage in the knee, useful in sports injuries and other sorts of ailments, is being tested with sheep, and they've got a small ear, designed by a dentist, who will attempt to implant in rats.

Source: elmundo.es

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smart drugs stem cell scientists alarm

British scientists warn a possible detriment of science and opinion of counsel, who said that using embryonic stem cells is against the ethics and public policy

The father of the sheep Dolly, Ian Wilmut, and other leading British scientists have expressed alarm at the general counsel's opinion of the Court of Justice against allowing the patenting of inventions based on embryonic stem cells human.

The man who cloned the first sheep and his colleagues argue that the French judge's legal opinion Yves Bot, the general counsel of the Luxembourg-based court, if accepted by the thirteen judges of the House, would mark the end of European research methods that could be used to cure degenerative diseases such as Parkinson's, among others.

In his opinion, he answered to the appeal by the owner of a German patent, the Advocate General pointed out that patents should be prohibited "an invention that uses embryonic stem cells " for its "industrial application" would using human embryos "as trivial matter, which would go against ethics and public policy. "

" Inventions relating to pluripotent stem cells can only be patented if not obtained at the expense of an embryo, whether for destruction or alteration "Bot said the judge in his legal opinion, which is not yet binding on the Court.

In strong reaction, reported today that the British newspaper The Independent, Ian Wilmut and twelve other leading researchers in the field of embryonic stem cells indicate that this legal opinion, if finally accepted, would in order to European research on embryonic cells.

"The general counsel's opinion is a threat to our research and European science in general. Patents are a key vehicle for providing new products for medical purposes," said Professor Austin Smith, president of the center Embryonic cell research Wellcome Trust at the University of Cambridge.

Professor Peter Coffey, a stem cell researcher at University College London, who expects to begin clinical trials to treat a type of blindness known as macular degeneration related to age, said banning such patents would allow U.S. and other European countries to exploit inventions in this sector.

According Coffey, the UK government has invested millions of pounds to create links between UK universities and pharmaceutical companies interested in developing therapies based on stem cells embryonic, all of which could endanger now the consequent negative impact on the economy of this country.

Source: eluniversal.com.mx

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The cord blood bank opens its inception with a donation

Delivery service Elche General Hospital launched yesterday, so and as planned, the bank collection of umbilical cord blood thanks to the donation of a woman giving birth before the relevant authorization made so they could extract samples. With this donation has been given the go-ahead to a service that already had been providing in several hospitals in the province and the members of the team had no intention of joining Obstetrics long.

The process begins with the informed consent of the mother after what the professionals come to the collection of umbilical cord blood at delivery in a process that takes no more than a few minutes. After removing the blood, it is stored in a refrigerator and in completing the necessary documents to accompany the bags to the Transfusion Centre of Alicante, being professionals in this center managers refer to the Bank Umbilical Cord Blood Center Transfusion of Valencia. At present, the staff is emphasizing that the information reaches all pregnant women to participate in the project if they so wish.

The umbilical cord blood is used, especially for stem cell transplantation bone marrow appears to give better results than adult implant.

Source: diarioinformacion.com

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stem cells into neurons

Researchers at the University of California in the United States have created c Elul mother can become various types of neurons avoiding the risk of forming tumors, according to a study published in the online edition of the journal Proceedings of the National Academy of Sciences' (PNAS).

Scientists have distinct neural these c Elul from embryonic stem cells . These cells, which have the potential to become in any body tissue, have seen limited use, mostly because of its potential to generate tumors.

addition to avoid this risk, the procedure used by researchers has created the cells in large quantities and are stable cell cultures is essential for its usefulness in the drug field.

explains Kang Zhang, head of the study and director of the Institute of Genomic Medicine, University of California, "we can quickly generate stable stem cells in large quantities (millions in less than a week), so that can be used clinical trials and, ultimately, treatments, something that until now was not possible. "

to generate neural stem cells, Zhang and colleagues added a series of small molecules with a chemical solution that induces cells embryonic stem cells to become neural precursors, but paralyzed the process before differentiation occurs. "As we do not use gene transfer technologies or exogenous cellular products, the risk of mutations or contamination is minimal," added Zhang.

This procedure allows researchers are able to make cells precursor showed no evidence of tumor formation when they are introduced into laboratory mice.

By adding other chemicals, scientists have been able to direct the differentiation of precursor cells into different types of mature neurons. Zhang notes that as meaning that we can explore possible clinical applications for a wide range of neurodegenerative diseases.

"You can generate neurons for specific disorders such as amyotrophic lateral sclerosis (ALS), Parkinson's disease or, in the case of my area of \u200b\u200bresearch, specific neurons eyes lost in macular degeneration, retinitis pigmentosa or glaucoma, "said Zhang, a professor of ophthalmology and human genetics at the Shiley Eye Center.

The new process suggests the possibility of wide applications in cell research mother. The same method can be used to induce pluripotent stem cells (stem cells derived from mature cells artificially differentiated adult) to become neural stem cells.

"And in principle, by altering the combination of small molecules could be created other types of stem cells able to become heart cells, pancreas and muscle, to name a few, "says the researcher.

Zhang concludes that the next step is to use stem cells to treat various types in animal models of neurodegenerative diseases such as macular degeneration or glaucoma.

Source: europapress.es

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Stem Cells for infertility

Stem Cells for infertility

Valencia .- The director of the Center for Education and Research with embryonic stem cells University Stanford, Renee Reijo, said that knowing the passage of cell gamete mother will prevent infertility.

Reijo, a leading researcher in the creation of artificial gametes from pluripotent stem cells has made these statements in the fourth International Congress of IVI, which until last Saturday met in Valencia to a thousand experts in assisted reproduction, according to a statement from the organization.

lines stem cells grown in the lab provide scientists the opportunity to use in treating diseases like diabetes, obesity, Parkinson and infertility.

Renee Reijo

According to the development of diseases like cancer or Parkinson 'occurs at some point in the stem cells become specialized cells "and the current challenge is to understand this process identify the key moment and to act to prevent further development. "

"We've already covered half the way in creating artificial eggs and sperm, but we need further research to achieve better quality gametes," said Reijo, who added that this would allow "the creation of gametes Patients who do not have them, that could avoid the donation. "

The Center for Education and Research with embryonic stem cells at Stanford University is also investigating another potential application of stem cells: making cells and tissues for medical treatment, so that People who need a transplant to resort to its own cells and, thus, prevent transplant rejection posed.

Moreover, the president of IVI, Antonio Pellicer, has said that in assisted reproduction "challenge is making life more comfortable for the patient through the humanization Maximum treatments. "

According Pellicer, mimic the natural conception process passes to avoid multiple pregnancies and ovarian hyperstimulation, which has virtually disappeared with the new drugs.

" The major cause of abandonment in assisted reproduction treatments is stress, mainly due to the medication, and is now moving from daily injections to oral drugs, which standardizes the process of looking for a baby to the patient, "says Pelletier.

Finally, Pellicer has stressed the importance that had in recent years the clinical application of vitrification prevents the woman to have more of a process of ovarian stimulation.

Source: EFE

Stem Cells for infertility

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umbilical cord stem cells to treat lupus

umbilical cord stem cells to treat lupus

Researchers at National Yang- Ming University, Taiwan, China, ensure that mesenchymal stem cells derived from umbilical cord blood may represent a new therapeutic alternative for the treatment of nephritis Lupus, a major complication of systemic lupus erythematosus.

This follows from the results of a study in mice whose results are published in its latest issue, the journal Cell in Transplantation. "

explains the study's lead author, Dr. Oscar K. Lee, these cells have been shown to possess immune-modulating capacity that allows them to relieve the body's immune response by inhibiting inflammation and immune response of T cells

Lee and his team tried to analyze the therapeutic effects of these cells in the treatment of lupus nephritis. They used a mouse model for transplantation of cord blood cells, having proved effective in other immune system diseases.

Thus, as explained, "have shown that transplantation causes a marked delay the deterioration of renal function, reduces levels of certain antibodies, relieves the changes in renal disease and the development of proteinuria, a sign of kidney damage. "

also observed a positive difference in survival rates of mice were treated with two months of life compared with those rodents than six months old, which has led researchers to believe that early transplant may be more effective.

The researchers also opt for the option of an allogeneic transplant and non-autologous (patient's own cells), under the therapeutic effects observed in this study.

"The ability of these cells to reduce inflammation shows that it is likely to be useful for treating autoimmune diseases and this study supports this argument," said David Eve, associate editor of 'Cell in Transplantation. "

Source: europapress.es

umbilical cord stem cells to treat lupus

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Stem cells are to cure many diseases

The stem cells will cure many diseases

The head of the Hematology Service of the Hospital de Palencia, Fernando Ortega, has given a lecture organized by the School of Pastoral Care, entitled "Controversies in the therapeutic use of stem cells."

- What are these disputes?

"The stem cell issue is very controversial for its own origin. There are two types of stem cells. Some are embryonic and other stem cells adult. These do not pose ethical problems because they are cells taken from adult human. However, the embryo are those obtained from studies done of fertilization in vitro, surplus to assisted reproduction. These embryos are used to obtain stem cells, and in consequence they are destroyed. Embryonic stem cells have great potential differentiator to transform into other tissues are unstable and easily develop tumors which are implanted. There are no clinical trials to investigate its use in humans, only animals. They have won the battle of adult stem cells, which have a similar behavior to embryonic, but are safer and do not develop cancers and tumors.

- A Catholic can accept the use of this type of progress with stem cells?

"I understand that a Catholic can not accept the fact of destroying an embryo because the embryo is a living being and a human. With stem cell research on embryos are destroyed thousands, which for a Christian is unacceptable.

- What are the drawbacks stem cells.

"The research is very slow, because the manipulation of cells is always complex, many problems arise, as to be maintained in culture cells and then begin testing in animals (mice, pigs, rabbits ...) to finally decide to use in humans. Stem cells are going to lead a revolution and will cure many diseases. However, take time to stem cell therapy is useful.

- Are you in favor of therapeutic use?

-Partisan with adult stem cells, not embryonic stem cells, which are forbidden even by most governments.

- How far will science?

-Science always opens the right track. Genetic manipulation and cloning of human beings, which is reprehensible, I am convinced that science is going to stop. Science seeks the ultimate way to solve the problems that human beings really are, which include health.

Source: The

nortecastilla.es stem cells will cure many diseases

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know the passage of a stem cell to prevent infertility

know the passage of a stem cell gamete to prevent infertility

Director of Centre for Education and Research with embryonic stem cells at Stanford University, Renee Reijo, said that knowing the step of gamete mother cell to help to avoid infertility.

Reijo, a leading researcher in the creation of artificial gametes from pluripotent stem cells has made these statements in the fourth International Congress of IVI, which until last Saturday met in Valencia to a thousand experts playing assisted, according to a statement from the organization.

stem cell lines grown in the lab provide scientists the opportunity to use in treating diseases like diabetes, obesity, Parkinson and infertility. According to Renée

Reijo, the development of diseases like cancer or Parkinson 'occurs in a time when stem cells become specialized cells "and the current challenge is to understand the process to detect the key moment and to act to prevent further development. "

"We've already covered half the way in creating artificial eggs and sperm, but we need further research to achieve better quality gametes," said Reijo, who added that this would allow "the creation of gametes in patients not have them, which could prevent the donation. "

The Center for Education and Research on cells embryonic stem Stanford University is also investigating another potential application of stem cells: making cells and tissues for medical treatment, so that people who need a transplant to resort to its own cells and, thus, avoid rejection involving transplants.

Moreover, the president of IVI, Antonio Pellicer, has said that in assisted reproduction "the challenge is to make life more comfortable for the patient through the full humanization of the treatment." According

Pellicer, mimic the natural conception process passes to avoid multiple pregnancies and ovarian hyperstimulation has virtually disappeared with the new drugs.

"The major cause of neglect in assisted reproduction treatments is stress, mainly due to the medication, and is now moving from daily injections to oral drugs, which standardizes the process of looking for a baby to patient, "says Pelletier.

Finally, Pellicer has stressed the importance it has had in recent years the clinical application of vitrification prevents the woman to have more of a process of ovarian stimulation. Source: EFE

know the passage of a stem cell Gamete to prevent infertility

Scientists achieve

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gamete Scientists fail to generate neurons from stem cells

generate neurons from stem cells

A group of U.S. scientists has succeeded for the first time, generating neurons from stem cells with induced pluripotent (iPSC) in patients with schizophrenia. The results of this work, published this week in Nature, show that neurons generated from iPSC cells of schizophrenic patients are able to generate fewer neural connections than the rest.

This research, led by Fred Gage, Professor, Laboratory of Genetics at the Salk Institute in California, U.S., has discovered that an antipsychotic drug commonly used to treat this disease, loxapine, is able to restore the connectivity between these new cells and also affected the activity of hundreds gene.

To make this work, scientists reprogrammed skin fibroblasts from four schizophrenic patients with a hereditary predisposition to the disease. The authors differentiate these reprogrammed cells (iPSC) in neurons.

then used a modified rabies virus to highlight the connections between neurons, allowing to detect the differences between neurons from normal and schizophrenic patients.

With the viral tracer observed that the neurons of patients were connected to each other less often and had fewer projections grow out from their cell bodies. For its part, the gene expression profiles identified almost 600 genes whose activity was poorly regulated in these neurons.

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During the last three weeks of cell differentiation, the researchers administered a series of drugs commonly prescribed antipsychotics. Loxapine was the only one who acted on dopamine receptors in the brain, increasing the ability of neurons to reach out to their neighbors' and to connect. This drug also affected the activity of hundreds of genes.

Experts expect that this new model is useful for designing new drugs against this disease, which affects 1 percent of world population.

As explained Gage SINC statements gathered by Europa Press, describing the biological mechanisms underlying this disease is "a major step in the research field because for many years been considered a disease only 'social' "." It is true that the environment affects schizophrenia, but there are a lot of components that are genetically determined, "he says.

However, it remains without knowing the root cause that generates schizophrenia. "Without a minimal understanding of the causes and pathophysiology of this mental disorder, we lack the tools necessary to develop effective treatments or preventive measures," he says.

Source : Scientists

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Stem Cells, a promise against diabetes

Stem Cells, a promise against diabetes

The stem cells help treat diabetes in "ten or fifteen years", as the director said Friday Department of Stem Cell Development in Miami, Juan Domínguez-Bendala, who participated in the XXII National Congress on the disease to be held in Malaga, a meeting also attended by the researcher and former health minister, Bernat Soria.

Domínguez-Bendala

explained that "although our intention is to expand rapidly" treatment with stem cells, "we can never give an exact date until we have the safety and efficacy sufficient." "The use of stem cells is very important because they are immortal cells and readily available but must be stressed that provide insulin cells that are not as easy to generate other," he explained.

The former minister has referred to the different cell therapy clinical trials being carried out in Andalusia, "who has been a pioneer in this field." For the moment, has conducted a trial with patient's own stem cells to avoid what is known as diabetic foot, which results amputation of the same. According to Soria, the results of this test, performed on 20 patients of Andalusia, has been positive and "not only prevented the amputation but they have improved the health of the sick."

However, this treatment is included as one of the benefits offered by the health system, Soria explained that "still have to study in hospitals across the country and follow up to last two to three years in all patients to have all the assurances that offer a safe and effective treatment. "

Finally, he noted that currently being undertaken, in several hospitals present another set of trials with various types of cells, "we will post results when they are completed."

According to recent studies by the World Health Organization (WHO), there may be more than 220 million people with diabetes worldwide and within 15 or 20 years this number may exceed five hundred million people affected. Furthermore, in Spain, more than 13.5% of adults have diabetes and many others at risk of developing diabetes by high glucose levels recorded due to the increase in unhealthy lifestyles, commented Friday el ex ministro de Sanidad, Bernat Soria.

Estos datos, extraídos del primer estudio estatal sobre esta enfermedad, ponen de maniesto que "la salud pública debe tener en cuenta tanto a la diabetes como a los problemas que ésta conlleva", ha indicado Soria asegurando que "si queremos aumentar la salud de los españoles tenemos que investigar y estar comprometidos con todos los campos".

Fuente: elmundo.es

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The boy Joel improvement after stem cell transplantation

La concejala de Solidaridad, Remedios Herrero, ha recibido al niño y al padre para felicitarlos by resultados.La family thanked the people of Benalmádena has provided collaboration in actions aimed at raising funds.

Councillor Solidarity, Remedios Herrero, received this morning, Joel Ortega, the child Benalmadena which have managed to raise enough funds so it can be operated in an intervention that has been made in Germany reduce the incidence of cerebral palsy being treated. Marcelo Ortega, Joel's father, explained that since the intervention, taken last February, the child has experienced some improvement, as it has reduced pain and increased expression.

Marcelo Ortega thanked the people of Benalmádena deep collaboration that has paid in actions aimed at raising funds and to City Council and the Councillor of Solidarity, "who have spread these actions so that the neighbors involved," . In addition, explained that the improvements will be produced as the months have elapsed since such recoveries are slow.

Meanwhile, Remedios Smith has congratulated the family of Joel and achievements, and he has delivered some gifts to the child. "I am pleased today to see Joel after having been operated successfully, thanks to support and affection of all who have contributed to this improvement a reality, "said the mayor.

Benalmadena

Little, 13, has been undergoing a transplant of stem cells that will reduce cerebral palsy by 70 percent and give him the chance to speak, pick up objects with hands and, at best, to walk. The intervention and the cost of it has come at a cost of 9,000 euros.

Source: benalmadenanoticias.es

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retina Crean mouse stem cell

Japanese scientists announced the creation of a retina in the laboratory from embryonic cells, which is an important step for the treatment of diseases of this tissue, even some forms of blindness.

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public banks in Spain

public umbilical cord banks in Spain

Storing cord blood takes place in public banks umbilical cord, of which there are seven approved in Spain , specifically: Barcelona

• Galicia
• Madrid Malaga Tenerife
• Asturias Valencia

Subsequently, the blood is used for stem cell adult obtained from umbilical cord fluid, a more effective alternative to traditional bone marrow transplantation, decreasing the likelihood that there is a rejection and improves and accelerates the clinical outcome.

The umbilical cord blood has not only hematopoietic stem cells (capable of forming several types of blood cells), but also has mesenchymal stem cells, which may allow the creation of cells neural, bone cells, heart muscle and other muscle cells.

umbilical cord blood has the ability to regenerate the bone marrow and immune system when it is depressed, either by a disease of the bone marrow, or by a previous chemotherapy treatment (used as conditioning prior to the preparation of the patient to be transplanted with hematopoietic stem cells).

The results of numerous clinical trials in recent years indicate that there is less chance of having a transplant rejection if used by umbilical cord blood.

According to scientists, the most likely reason for this is that immune system cells of the newborn are less developed than adults. Have set up banks that store cord for use in transplants for people compatible.

Source: diarioinformacion.com

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umbilical cord blood bank umbilical cord in Elche

The General Hospital of Elche has already prepared the necessary procedures to implement the bank collecting umbilical cord blood , a practice that with the approval of the general direction of management, Health Assessment and Research of the Department of Health since last September, but a few days ago that the center has the necessary refrigeration equipment to conserve the liquid.

Therefore, the center plans to start Elche withdrawals from next Monday between the mothers who so wish. "Pregnant women are informed of this possibility by midwives in the health center, which will give all the information and are seek informed consent. Here is where women decide what they can collect the cord blood and cases where it is contraindicated, for example, among women who suffer from some diseases, including those that have given birth less than 34 weeks of gestation or in multiple pregnancies, "said Alfredo Millá, section chief in the area of \u200b\u200bObstetrics General Hospital Elche.

Therefore, service members of Gynecology and Obstetrics and Haematology, key stakeholders in carrying out this process, last week attended a training lecture given by Dr. Pilar Solbes, member of the Center Transfusion of Valencia and the seat of Cord Blood Bank , which will target the extractions carried out in Elche. Solbes told the audience the various protocols for action and documentation required to perform the extractions.

The extraction of the blood does not take more than a few minutes and once obtained it will be stored in a refrigerator and completed documents required to accompany the bags to the Transfusion Centre of Alicante, with professionals of this organism in charge of forwarding them to Bank Umbilical Cord Blood Transfusion Center Valencia.

Team members are expected Elche daily blood collection and forwarding it to the end of each day Transfusion Center for storage and use anywhere in the country. "It's important that mothers are aware that this type of donation not mean having the cord itself for future children, but will be autonomous transplant coordinators who identify potential recipients of blood in our country or abroad. The umbilical cord blood will be used for clinical or therapeutic use and research, "said Miller, who stressed that the process of cord blood collection is not only available of pregnant women assigned to General Hospital but to all women who want to make the donation and that, therefore, may give birth in the middle of the street gardens and Mills.

The refrigeration unit is already physically in the hospital delivery area of \u200b\u200bElche, where he recorded a daily average of four or five deliveries. The importance of collecting cord blood is that it contains stem cells that are vital for the renewal of blood cells in patients who have impaired bone marrow.

Once in the Community and four in the province

The Valencian Community has at present eleven hospitals that are approved for the extraction of umbilical cord blood, and of these, four are in the province of Alicante. Specifically, the centers licensed to perform these extractions are La Fe, La Ribera, La Plana, The Clinic, Doctor Peset, Lluis Alcanyis, General de Castellón, General de Alicante, San Juan de Alicante, Hospital de la Vega Baja (Orihuela) and Hospital de Torrevieja. They will be joined on Monday the General Hospital of Elche which takes months to manage the relevant authorization from the Department of Health, as unwieldy accreditation requires permits to confirm the ability of the clinic in question to perform the extractions. The last step was the purchase of refrigeration equipment in the hospital Elche store the blood until the time comes to be forwarded to the Transfusion Centre of Valencia.

Source: diarioinformacion.com

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Establish stem cell line to study genetic disorders Crean first heart

The University of Michigan established the first line in that state of stem cells from embryos carrying genes responsible for inherited diseases, which will study the onset and progress of genetic disorders and the search for new treatments.

This University of Michigan (UM) joined the small group of U.S. universities with this specific lines for certain diseases, which has called UM9-1 and UM11-1, developed by researchers at the Consortium for Therapies Stem Cells institution.

UM9-1 line carries the genetic defect that causes hemophilia B, a hereditary condition in which blood does not clot properly.

While UM11-1 is carrying the disease gene responsible for Charcot-Marie-Tooth disease, an inherited neurological disorder characterized by degeneration progressive muscle of the foot, lower leg and hand.

Both are the only lines in the Federal Register carriers of these three genes for specific diseases that exist in the same register, which contains 91 lines of human embryonic stem cells, the university said.

To obtain the UM is based on Michigan law states that if human embryos created for reproduction but were found not suitable for such use because they carry disease, are donated for research Instead of being destroyed.

In the months and years following the embryos donated will be used, for example, to create cell lines that carry the genes responsible for myotonic dystrophy, Huntington's disease, Rett syndrome, spinal muscular atrophy and Tay-Sachs evil .

The consortium will distribute samples UM9-1 and UM11-1 to researchers around the campus and statewide partners and the National Institutes of Health United States for inclusion on the National Register lines of human embryonic stem cells eligible for federal funding of research.

These are the second and third lines of human embryonic stem cells developed by the consortium, after UM4-6 was announced in October and was derived from an embryo of five days, normal genetically created for reproductive purposes but no longer be necessary for this was donated to UM.

The creation of the three lines was possible because Michigan voters in November 2008 approved Proposition 2, a state constitutional amendment which allowed scientists to derive stem cell lines using embryos left over from the clinics fertility.

The amendment also allowed collaboration between UM and the Genesis Genetics Company, based in Detroit, the leading global provider of genetic diagnostic testing prior to implantation.

These tests are tests to identify embryos a few days, carriers of genetic mutations that are responsible for hereditary diseases.

Genesis Genetics held every year nearly four thousand examinations and following the agreement with the university patients with embryos that are positive for a genetic disease have the option of donating those embryos to UM Consortium.

Source: informador.com.mx

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laboratory

used a donor heart, which used only its external structure. Then it was repopulated with stem cells receptor potential.

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human stem cell stem cell bank in Canary

Canary

points health at the forefront of the country, with the inauguration in a few months bank umbilical cord blood and setting up a milk bank, which is scheduled for 2012, announced yesterday the president of the Institute of Blood Donation and Hemotherapy Canario, Jose Gilberto Moreno.

At a meeting in Las Palmas de Gran Canaria with the media to report the data for blood donations in the Islands for the period from 2010, which was attended by the regional director of Health, Fernando Banyoles, Moreno explained that the facilities of the Institute for Blood Donation and Hemotherapy are being remodeled in the two provinces "to launch a new laboratory and continued to incorporate into our donation activity umbilical cord blood, breast milk and other tissues. "

Stem cells and breast

" Having a bank stem cells is an important development in the Canary Islands hope for the research and cure of many diseases, "said Moreno, who also recalled that" there was a pioneering "blood storage of stem cells" in a hospital in La Candelaria, Tenerife, although the activity stalled at the expense of crediting the hospitals canaries as extraction centers.

In this regard, Moreno emphasized that these storage points stem cells must be coordinated with existing state-level "in order to collect the greatest number of possible phenotypes," he said, and cover a range over comprehensive genetic characteristics of the inhabitants of all regions.

Institute President Canario Hemotherapy Blood Donation and also stressed the importance of implementation of a storage bank breast milk, a pioneer in the Canary Islands, for women who are not in a position to breastfeed their children, creatures that must be between zero and two años para beneficiarse de este avance.

La leche materna deberá mantenerse a -80 grados en los almacenes del instituto canario, para lo cual se irán efectuado reformas en sus sedes, "algo que está sujeto a los tiempos económicos", según Gilberto Moreno, "porque estos servicios precisan de unas reformas importantes en ambas sedes". El personal del Instituto Canario de Hemodonación y Hemoterapia deberá recibir también la preparación necesaria para desarrollar correctamente su labor.

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Por otro lado, Bañolas destacó que en materia de donación Blood Island "has been a slight decrease of 1.48% over the past 2010" with respect to the previous annuity, in which there were 69,457 voluntary withdrawals compared to 70,502 in 2009.

The Minister linked this fall "with the decline in donations in the hospitals of the province of Las Palmas, estimated at -7.35% - and falling out of hospital donations in a -7.66% in the province of Santa Cruz de Tenerife. "

The Minister also noted that were Gran Canaria and Lanzarote islands where there were more grants and also indicated that despite the decline "canaries centers are supplied "blood for the interventions they need.

In 2010, he added Banyoles, have increased by 0.75% people who donate two or more times per year and reduced donations from people aged between 25 and 40, who until last year that more blood was donated.

Source:. laprovincia.es

Stem Cells

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Myths and facts about cord stem cells

Stem cells are cells capable of developing into any of the 220 different types that exist in the body through intracellular signals according to the expressed needs of the human body every day.

the Venezuelan Chamber of Cryopreservation of Stem Cells (CVCCM) trade organization nonprofit that brings together private banks storage stem cells, recently gave a workshop for journalists entitled "Myths and facts about stem cells, "in order to bring the social media real information about what stem cells are, what their collection and cryopreservation process, what are the recommended uses and primarily to break down the myths surrounding them.

The workshop was led by Dr. Adriana Lopez, cell biologist and PhD in Life Sciences and Health, and the international guest Doctor Naynesh R. Kamani, a doctor with 28 years experience in transplants and representative of the National Marrow Donor U.S., also speaker of the XXVII Congress of Gynecology and Obstetrics, held in Caracas in March this year. The experts discussed and explained on the main beliefs that stem cells exist, their extraction, use and real potential therapies or treatments.

Myth 1: validated treatments currently on

Currently, stem cell transplantation is validated as a possible treatment of hematologic diseases origin. These include: the different types of leukemia, lymphoma, congenital abnormalities of red blood cells (responsible for carrying oxygen to the body), anemia, congenital abnormalities of platelets (necessary for healing), congenital immune system disorders, phagocytic disorders ( phagocytes can trap and destroy foreign bodies), bone marrow cancer and other cancers. About 80 kinds of conditions can be treated with stem cells, however, the success of the procedure depends on the degree of compatibility that exists between the donor and recipient, in addition to the state in which the disease is, among other factors.

Myth 2: on the collection and cryopreservation

The resource describes the procedure for extracting cord cells as a completely painless procedure, both mother and baby, and that the umbilical cord no nerve endings, as opposed to implying extraction stem cells of the spinal cord, which is invasive and painful. "Once the baby is born and being completely out of danger he and the mother, there is the collection of the sample," he explains. Dr. Adriana Lopez asserts that as a result of technology that are currently available, samples can be cryopreserved and preserved in optimum conditions for up to 20 years.

Myth 3: on Stem Cell Transplant

But for the newborn, the storage of stem cells is a potential safe for your family, these cells are used successfully heterólgos treatments (between people with similar genetic loads) for the high degree of compatibility between members of the family group, which "reduces the risk associated with rejection and other adverse reactions caused by the transplants," explains the Drs.

To achieve a successful transplant, the number of kilos and cells should be directly proportional. "In most cases, the cells taken from an umbilical cord are not enough to be transplanted into adults," Dr. Lee states, "However, recent pilot studies have been used or attached cells taken two umbilical cords, for use in these patients, which leads to the amount required for them. "

Source: diarioeltiempo.com.ve

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"Do not be overwhelmed by life" Mt 6, 24 to 34

OCTAVO DOMINGO T. O.   CICLO A

 

" No estéis agobiados por la vida" . Mt. 6, 24 – 34

 

Con estas palabras Jesús nos invita a vivir en una confianza total en Dios, la misma que El vivía. Es esa confianza la que nos permite dejar en segundo plano los afanes y preocupaciones de la vida cotidiana (comida, dress, the future ....). overwhelmed The word appears six times. This bespoken translates a Greek verb that means something captures our hearts.

"Do not be overwhelmed by life thinking about what you will eat, or body thinking how you are going to wear."

is very likely that Jesus addresses these words to the group of disciples who had left everything to follow. The concerns of life had passed for them to be of secondary importance, because the Kingdom of God had become the most important. And from that choice and experience, you can live in the area of \u200b\u200babsolute trust in the Father who watches over all and knows our needs. He who cares for the birds and flowers of the field, take care with much more reason for all of us and every human being.

"Look at the birds: do not sow or blind, or store ... fiaos how the lilies grow: not labor or spin."

This message of the birds of the air and the lilies of the field has made us smile a lot, they say you have to be realistic. In fact, Jesus does not invite the negligence and irresponsibility. Jesus says not to worry, worry, live in distress. Trust opposes the anguish, the anxiety and obsession of wanting to control everything. The believer is fully trusts the Father's love, but still working.

"USCAR B first the kingdom of God and His righteousness ." The key to this message, it is essential to Jesus' seek first the Kingdom of God and His righteousness "and this is just a call to change from the root of these situations and the economic and social system that engenders. And when we do, that is, when we focus on the essentials in our lives, then we experience and live the Gospel as Good News.

what we use to have to eat if as individuals we waste?, What do we need to dress well and the last if we are empty inside?, What serves us well overwhelmed if we lose the essential thing?. Jesus insists that the former is the Kingdom: the radical change of man and the systems that generate dehumanization.

In short, the insistent invitation of Jesus to live not overwhelmed by the different concerns of life, no longer produces men and women of today, the impression of naivety and lack of realism. But perhaps we could ask but we who are not living in a totally wrong.

We take for granted in order to ensure happiness, we must have things, money, comfort, success, but experience tells us that, in fact, that way, we find exactly what we wanted: things, money, comfort, but not necessarily find happiness.

"You can not serve God and money." This is the central finding of Jesus in the Gospel of this Sunday. Why should we continue to develop the cult of money as the only god that offers security, power and happiness?

neoliberal model, we are immersed, it enriches a few at the expense of the poverty of many. Neoliberal globalization and postmodern culture have promoted a model of society based primarily on an economic value. Has created a culture marked by a fierce individualism, where appearance is better than reality, the transient more permanent, rather than exteriority and interiority where, above all, the be worth more than be .

The problem is not resolved to seek new sources of satisfaction. The problem is not resolved by compensating our empty ... On the contrary, every time we make our happiness depend more and more, that happiness is even more problematic and uncertain, because there are increasingly more likely that something fails us again and leave us dissatisfied and empty. Then it grows in us the tension, unrest, the exhaustion, and frustration. Would not it be more realistic to follow the instructions of Jesus: search every time the kingdom of God and His righteousness and not overwhelm both the morning? Would not it be better if they would welcome each day, each sunrise as a gift and an opportunity to move forward in our lives?

live a very opportune time to ask: What kind of society we want to build national and global so deep in this crisis we are experiencing?

Perhaps our prayer today might be: Lord wake us up to the trust. Live not so worried and obsessed about things ... You that you take care of the birds and flowers of the field, give us first look your kingdom and your righteousness. Lord Jesus, put your hands in our present and our future, our lives and our needs. You who are our treasure and our heritage forever.

Benjamin Garcia Soriano

February 27, 2011