laboratory
used a donor heart, which used only its external structure. Then it was repopulated with stem cells receptor potential.
Tuesday, April 5, 2011
Does Plato's Closet Sell Polo
Next week will be key to the research that has generated more buzz in the last year. This is creating the first human heart in a laboratory produced from stem cells. "The heart is growing and we hope to show signs of beats within the next week," said Doris Taylor, an academic at the University of Minnesota, who led the research, as slogan Sunday Times.
This is the first time achieved create a human organ with this technique. In the past, U.S. researchers had used to create a lung and liver, but in mice, while in the Wake Forest Institute succeeded in creating human urethra and bladder, but artificially generating collagen structures, where stem cells injected.
The procedure followed by Taylor's team consisted of taking a heart taken from a donor (deceased), which was washed with chemicals to remove the cells that formed cardiac muscles. Thus, only the structure of the body was composed of collagen fibers.
In parallel, the scientists extracted stem cells from the potential donor and cultured in the laboratory. Then these cells were injected into the collagen structure, for them to become heart muscle cells and repopulate the new "heart" stage, so far, been met smoothly.
The next challenge is to achieve the heart beating on its own. "We are far from creating a heart for transplant, but we believe we opened the door to the creation of any human organ for transplantation, "says Taylor.
Why this method for the creation of organs is in vogue? On the one hand, is an alternative that would use or diseased organs in poor condition, which currently are discarded because they used to be transplanted. That is, would extend the supply of organs available for transplant. In Chile, according to the Corporation of transplantation, 50% of patients who are in the waiting list for a heart dies before he can get one.
But just as important is the fact that using stem cells from the patient receiver to replace the original organ, reduces the likelihood that when the tissue is implanted in the recipient, your body rejects it, so that the patient would have a better prognosis recovery.
The creation of a human heart in this technique is a qualitative leap for the future development of new tissues and organs with stem cells. This, for the manufacture of a bioartificial heart was a greater difficulty level. Unlike the liver or lung, the heart requires the coordinated movements of various structures, as the valves where blood enters and exits in addition to the cavities through which circulates inside. A challenge could be overcome if next week the heart created in laboratory specialists behaves as expected: late.
"My prediction is that in the future will be possible to grow whole organs for use in transplants," reflects Taylor
Source: diario.latercera.com
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